Pyridazines. I. Novel Intramolecular Cycloaddition of 3-Chloro-6-(2-allylphenoxy) pyridazines
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Radicalic Ethoxycarbonylation of 3-iodo- Pyridazines: an Efficient Access to Tri- and Tetrasubstituted Pyridazines
Introduction of ester groups into positions 4 and 5 of 3-iodopyridazines (1,2) by redox decomposition of the oxyhydroperoxide of ethyl pyruvate in a sulfuric acid/toluene two-phase system affords trifunctional pyridazine building blocks (3,4a) in a single step. Iodoarenes and -hetarenes are known as useful synthons for C-C bond formation by palladium-catalyzed cross-coupling reactions. In the p...
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The synthesis of new heterocyclic oligo(phenylene) analogues based on soluble, nonaggregating 1,2-diazines is reported. Improved palladium-catalyzed reductive coupling methods were developed to allow for the preparation of large quantities of iptycene-derived bipyridazines and biphthalazines, and the controlled synthesis of well-defined oligomers up to sexipyridazine. Crystallographic, spectros...
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Intramolecular formal [4+2] cycloaddition between 3-ethoxycyclobutanones and a carbon-carbon double bond to the corresponding bicyclo[4.n.0]alkan-2-one derivatives proceeded effectively by using ethylaluminium dichloride.
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1972
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.20.2191